IT Senior Enterprise Architect, AI - Remote

About the position This position is a 100% remote within the United States, however, incumbent may be asked to come onsite once a month. At Mayo Clinic, we are transforming healthcare through bold innovation and we are seeking a Senior Enterprise IT Architect – AI to help lead that transformation. As a strategic leader within the Office of the CTO, you will shape and advance our enterprise AI architecture, enabling cutting-edge capabilities that directly improve patient care, research, and operational excellence. This role operates at the intersection of technology vision and real-world impact, designing scalable, secure, and ethical AI platforms that support clinical decision support, predictive analytics, generative AI, automation, and emerging intelligent systems across a world-class healthcare enterprise. The ideal candidate is a forward-thinking architect who combines deep enterprise architecture expertise with hands-on knowledge of AI/ML ecosystems, cloud-native platforms, data strategy, governance, and responsible AI practices. You will partner with executive leadership, clinical innovators, data scientists, engineers, and security teams to define reference architectures, standards, and roadmaps that accelerate AI adoption while ensuring compliance, reliability, and trust. This is a high-visibility opportunity to influence enterprise-wide strategy and deliver meaningful, mission-driven innovation at one of the most respected healthcare organizations in the world. Takes overall responsibility for developing a key area with strategic impact or scope of Enterprise Architecture framework or practice. Provides guidance to Enterprise and IT Architects and others as appropriate and serves as principal advisor to the Chief Architect and IT Executive Leadership on this key area. Monitors and incorporates into the practice, as appropriate, industry trends and opportunities in Enterprise Architecture. May also be responsible for technical architecture and recommendations in one or more information technology domains. Works to ensure that appropriate processes and communications are developed or modified to maintain the key framework or practice, and that the technology objectives and solutions of the enterprise are aligned to the business mission, strategy, goals, and processes. Establishes and communicates a technology vision within an Information Technology discipline. Builds a critical mass of support at all levels of the organization and across departments for a given technical direction through talks, articles, blogging, demonstrations, or interpersonal communication. Participates in major technical decisions, develops technical proposals that consider alternatives and business case, gains needed institution approvals, and works effectively across departmental organizations gaining consensus of stakeholders. Possesses and maintains a strong working knowledge of multi-platform technical environments. Serves as a leader, consultant, mentor, or tutor in many specific technical architecture areas of expertise to staff throughout the Department of Information Technology (IT). Assigns tasks to staff taking into consideration workload balancing, skill sets, technical knowledge, and criticality of the tasks. Serves on appropriate committees and acts as a resource to institutional committees on an ad hoc basis. Provides consultation in their area of expertise and facilitates institutional work groups. Leads committees to establish technical standards, promote integration of data, and/or coordination of projects across work units. Provides key input to short and long-term department strategy and budget planning. Must be customer focused and possess excellent communications and interpersonal skills to interact with a variety of personnel at various levels within and outside the institution. During the selection process you may participate in an OnDemand (pre-recorded) interview that you can complete at your convenience. During the OnDemand interview, a question will appear on your screen, and you will have time to consider each question before responding. You will have the opportunity to re-record your answer to each question - Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member and you will be notified of next steps. Responsibilities • Takes overall responsibility for developing a key area with strategic impact or scope of Enterprise Architecture framework or practice. • Provides guidance to Enterprise and IT Architects and others as appropriate and serves as principal advisor to the Chief Architect and IT Executive Leadership on this key area. • Monitors and incorporates into the practice, as appropriate, industry trends and opportunities in Enterprise Architecture. • May also be responsible for technical architecture and recommendations in one or more information technology domains. • Works to ensure that appropriate processes and communications are developed or modified to maintain the key framework or practice, and that the technology objectives and solutions of the enterprise are aligned to the business mission, strategy, goals, and processes. • Establishes and communicates a technology vision within an Information Technology discipline. • Builds a critical mass of support at all levels of the organization and across departments for a given technical direction through talks, articles, blogging, demonstrations, or interpersonal communication. • Participates in major technical decisions, develops technical proposals that consider alternatives and business case, gains needed institution approvals, and works effectively across departmental organizations gaining consensus of stakeholders. • Possesses and maintains a strong working knowledge of multi-platform technical environments. • Serves as a leader, consultant, mentor, or tutor in many specific technical architecture areas of expertise to staff throughout the Department of Information Technology (IT). • Assigns tasks to staff taking into consideration workload balancing, skill sets, technical knowledge, and criticality of the tasks. • Serves on appropriate committees and acts as a resource to institutional committees on an ad hoc basis. • Provides consultation in their area of expertise and facilitates institutional work groups. • Leads committees to establish technical standards, promote integration of data, and/or coordination of projects across work units. • Provides key input to short and long-term department strategy and budget planning. • Must be customer focused and possess excellent communications and interpersonal skills to interact with a variety of personnel at various levels within and outside the institution. Requirements • deep enterprise architecture expertise • hands-on knowledge of AI/ML ecosystems • cloud-native platforms • data strategy • governance • responsible AI practices • customer focused • excellent communications and interpersonal skills Benefits • Medical: Multiple plan options. • Dental: Delta Dental or reimbursement account for flexible coverage. • Vision: Affordable plan with national network. • Pre-Tax Savings: HSA and FSAs for eligible expenses. • Retirement: Competitive retirement package to secure your future. Apply tot his job Apply To this Job